Strength and Hypertrophy

Should You Train to Failure for Muscle and Strength? (Research Review)
Learn when you should use failure training, and if it’s ideal for building muscle mass and strength. Based on a scientific literature review.



How Drop Sets Affect Strength and Hypertrophy (Research Review)
Drop sets are an efficient way to train, but are they better than regular sets for building muscle and strength? Find out in Sci-Fit’s review.



How Cluster Sets, Rest-Pause, and Drop-Sets Affect Strength, Hypertrophy, and Power (Research Review)
Many claim that cluster sets, rest-pause, and drop-sets are good for developing strength, hypertrophy, and power. But what does the literature have to say?



Gaining Muscle Mass in a Deficit vs. Bulking (Research Review)
Can we gain in a deficit? How much should you eat to reach your goals? This article applies to you whether you’re a beginner or advanced lifter.



Scientific Recommendations for Strength and Hypertrophy Training from 150+ Studies
What is the ideal frequency, rest period, exercise order, range of motion? Should we train to failure? Do we need to include isolation exercise into our program? We’ve analyzed 150+ studies to find out!



The Science of Detraining: How Long You Can Take a Break from the Gym Before You Lose Muscle Mass, Strength, and Endurance
In this article we answer how long it takes us to detrain (lose strength, conditioning, and muscle), and which strategies we can use to prevent it.



Using Science to Solve Overtraining: a Practical Guide Based on 190+ Studies
We have reviewed the scientific literature to give you an evidence-based way to prevent and treat overtraining.



Anabolic Resistance: Why it is Harder to Add Muscle Mass as We Age and How to Fight It
I think most of us have seen what can happen to the human body as it ages. Check this article out to find out how aging affects muscle mass and health. The article contains research-based recommendations from 60+ studies and reviews
Nutrition



The Fascinating Discoveries We Made in 2018
Understand how Sci-Fit works and how you benefit. Discover recent ketogenic developments. Learn what we are working on in 2019. Meet our collaborators.



Adhering to the Ketogenic Diet – Is it Easy or Hard? (Research Review)
We analyze ketogenic data to find out if people can stick with the ketogenic diet. We graph ketone levels, carb intake, and do a meta-analysis of dropouts.



Keto Flush – How Body Water and Glycogen Affect Ketogenic Weight Loss
The ketogenic diet is known for causing rapid weight loss. But, it also has dehydrating effects. Dig in as we explain what happens with glycogen, water, and salt. We give recommendations for preventing keto flush.



Do Ketone Supplements Enhance Performance? (Research Review)
Ketone supplements are said to boost athletic performance, burn fat, and have many other benefits. Sci-Fit has reviewed the scientific literature to examine these claims.



How the Ketogenic Diet Affects Hunger (Research Review)
Will the ketogenic diet suppress or increase your hunger? How does it compare to other diets? We have reviewed the scientific literature to find out if you will be hungry on keto.



How Keto Scientists Connect to Keto Companies (a critical investigation)
Learn what happens behind the scenes in ketogenic diet research. This article investigates the most prominent keto scientists and keto companies. We have looked into their conflicts of interest and funding sources.



How Carbs and Protein Affect Ketosis (Keto Research Review)
Do you need to eat less than 50 grams of carbs to be in ketosis? What about protein? We have analyzed the data from ketogenic research.



The Ketogenic Diet’s Impact on Body Fat, Muscle Mass, Strength, and Endurance
How does the Ketogenic Diet compare to other diets for improving your body composition and athletic performance? Read the article to find out.
Other



How Keto Scientists Connect to Keto Companies (a critical investigation)
Learn what happens behind the scenes in ketogenic diet research. This article investigates the most prominent keto scientists and keto companies. We have looked into their conflicts of interest and funding sources.



Why Study Results Don’t Always Apply to You (Research Limitations)
This article is a general introduction to the limitations of fitness and nutrition research. Learn what you can and can’t glean from research and how to apply it to your life.



Does mTOR Cause Hypertrophy?
Lauded as the source of all gains, mTOR has a big rep to live up to. In this article, we’re going to answer the following questions:
– What are the functions of mTOR?
– Can mTOR activation lead to hypertrophy?
– Are there situations where mTOR activation does not lead to gains?



Is Post-Exercise Hormone Secretion Linked to Gains?
Anabolic hormones are often said to enhance gains when they are secreted after exercise. However, this has not been supported by research.



Anabolic Signalling Mechanisms
Does muscle protein synthesis predict muscular gains?
Study Collections



Drop Set Study Collection
The drop set is an intense training technique used by bodybuilders. Yet, is it superior to regular strength training for strength and hypertrophy?



Cold Water Immersion – A Collection of 240+ Studies
Cold Water Immersion is used to improve athletic recovery and possibly performance. Topics include muscle soreness, fatigue, inflammation, and more.



Creatine Research – A Collection of 230+ Studies
Creatine research covers topics such as endurance training, high intensity training, muscle strength, hypertrophy, health, brain performance, diseases, and more.



Overfeeding and Overeating: A Collection of 70+ Studies
Learn about overfeeding and how it affects your body composition, energy expenditure, etc. Find the studies you want in this collection of research.



Energy Expenditure and Energy Balance: Collection of 300+ Studies
Read the science and learn how the body regulates energy expenditure. Topics: energy expenditure and balance, the afterburn effect (EPOC), RMR, NEAT, AT, TEF, & metabolic rates.



A Collection of 200+ Keto and Carbohydrate Studies
Topics covered: Weight loss and gain, keto vs. regular diets, carbohydrates, performance, muscle glycogen changes, diabetes, cancer, epilepsy, etc.



Collection of 70+ Bodybuilding Studies: Nutrition, Health, Contest Prep
These bodybuilding studies cover topics such as health, training, nutrition, contest prep, supplements, drug use, psychology, eating disorders, hormones, and more.



Collection of 450+ Weight Loss Studies: Appetite, Adherence, CICO, Meal Frequency, and More
Topics: artificial sweeteners, appetite, CICO, diet adherence, exercise, fasting, genetics, hormones, macronutrients, body weight maintenance, sleep, psychology, and more.



Collection of 300+ protein studies (hypertrophy, muscle protein synthesis, etc.)
Find the study you need in this huge collection of protein studies, reviews, and meta-analyses! Learn about muscle building, get practical advice, nutrition advice, and more.



Collection of 250+ Studies: Supplements, Vitamins, Bioavailability, Micronutrients
The studies cover health, athletic performance, strength, muscle mass, testosterone, cognitive function, dosages, and more. Topics covered: Arginine, Beta-alanine, Coenzyme Q10, Caffeine, Creatine, Citrulline Malate, Vitamin D, Ergogenic aids, Fish oil, Vitamin K1 and K2, bioavailability, Nutraceuticals, Nitric Oxide, and Pre-workouts.



Collection of Biomechanics Resources (Squat, Bench, Deadlift)
This article contains 31 videos, 39 studies, and other articles about your anatomy, biomechanics, individualization, physics, and exercise technique. The resources within can help you customize your squat, bench, and deadlift to fit your needs
Critical Study Analysis



Critical Analysis of McSwiney et al’s 2017 Keto Study
SCI-FIT presents a critical analysis of a ketogenic diet study. The study was published in 2017, by McSwiney et al.



Critical Analysis of Wilson et al’s. 2017 Keto Study
Wilson et al. just published a new keto study with incredible results. It has come under fire from experts due to its claims. I analyze the study in-depth.
Science Spotlights



Science Spotlight: Israel Halperin
Israel Halperin is a scientist that researches coaching, combat sports, metascience, and other fields. Learn about his top tips, watch his videos, and read his interview with Sci-Fit.



Science Spotlight: Grant Tinsley
Grant Tinsley researches intermittent fasting, nutrition, supplements, strength training, body composition, and more. Get to know Grant and his work here.



Science Spotlight: Alex Leaf
Alex Leaf is a science writer working for Examine.com. He writes about nutrition, health, fitness, and more. Get to know Alex through his interview, articles, and podcasts.



Science Spotlight: Brad Dieter
Brad Dieter is a researcher and science writer. He writes about fitness, nutrition, health, genetics, and more. Get to know Brad and his work here.



Science Spotlight: Brandon Roberts
Brandon Roberts is a coach, researcher, science writer, and bodybuilding physique competitor. Learn more about him and his work in this science spotlight.
Frequently Asked Questions
FAQ for the Ketogenic Diet
Written by: Adam Tzur (FB: SCI-FIT) Last updated: 25.10.2017 Do you have questions about the ketogenic diet? Send them to adam@sci-fit.net and the answers might be added to this FAQ. […]